2016
Improving combination antiretroviral therapy by targeting HIV-1 gene transcription. Expert Opin. Ther. Targets, 2016, 20: 1311–24. Accès à la publication
HIC1 controls cellular- and HIV-1- gene transcription via interactions with CTIP2 and HMGA1. Sci. Rep., 2016, 6: 34920. Accès à la publication
Targeting the Brain Reservoirs: Toward an HIV Cure. Front. Immunol., 2016, 7: 397. Accès à la publication
Reactivation capacity by latency-reversing agents ex vivo correlates with the size of the HIV-1 reservoir. AIDS Lond. Engl., 2016. Accès à la publication
Characterization of new RNA polymerase III and RNA polymerase II transcriptional promoters in the Bovine Leukemia Virus genome. Sci. Rep., 2016, 6: 31125. Accès à la publication
Protein Kinase C-Mediated Phosphorylation of BCL11B at Serine 2 Negatively Regulates Its Interaction with NuRD Complexes during CD4+ T-Cell Activation. Mol. Cell. Biol., 2016, 36: 1881–98 Accès à la publication
Tuning of AKT-pathway by Nef and its blockade by protease inhibitors results in limited recovery in latently HIV infected T-cell line. Sci. Rep., 2016, 6: 24090. Accès à la publication
2015
Sequential treatment with 5-aza-2’-deoxycytidine and deacetylase inhibitors reactivates HIV-1. EMBO Mol. Med., 2015 Dec 17 [Epub ahead of print] Accès à la publication
An In-Depth Comparison of Latency-Reversing Agent Combinations in Various In Vitro and Ex Vivo HIV-1 Latency Models Identified Bryostatin-1+JQ1 and Ingenol-B+JQ1 to Potently Reactivate Viral Gene Expression. PLoS Pathog. Accès à la publication
2014
[CTIP2, a multifunctional protein: cellular physiopathology and therapeutic implications]. Med Sci (Paris). Accès à la publication
HMGA1 recruits CTIP2-repressed P-TEFb to the HIV-1 and cellular target promoters. Nucleic Acid Research. Accès à la publication
Blockade of BFA-mediated apoptosis in macrophages by the HIV-1 Nef protein. Cell Death Dis. Accès à la publication
The many lives of CTIP2: from AIDS to cancer and cardiac hypertrophy. J Cell Physiol. Accès à la publication
2013
Pseudomonas DING proteins as human transcriptional regulators and HIV-1 antagonists. Virol J. Accès à la publication
CTIP2 is a negative regulator of P-TEFb. Proc Natl Acad Sci USA. Accès à la publication
Non-coding RNAs: novel players in chromatin-regulation during viral latency. Curr Opin Virol. Accès à la publication
2012
DING proteins, their biochemical and structural properties, and their ability to inhibit HIV-1 replication. Bull Acad Natl Med. Accès à la publication
Histone methyltransferase inhibitors induce HIV-1 recovery in resting CD4(+) T cells from HIV-1-infected HAART-treated patients. AIDS. Accès à la publication
The level of DING proteins is increased in HIV-infected patients: in vitro and in vivo studies. Plos One. Accès à la publication
Achieving a cure for HIV infection: do we have reasons to be optimistic? J Antimicrob Chemother. Accès à la publication
LSD1 cooperates with CTIP2 to promote HIV-1 transcriptional silencing. Nucleic Acids Res. Accès à la publication
2011
Genome-wide binding map of the HIV-1 Tat protein to the human genome. Plos One. Accès à la publication
Chromatin disruption in the promoter of bovine leukemia virus during transcriptional activation. Nucleic Acid Res. Accès à la publication
Human-Phosphate-Binding-Protein inhibits HIV-1 gene transcription and replication. Virol J. Accès à la publication
The AP-1 binding sites located in the pol gene intragenic regulatory region of HIV-1 are important for viral replication. Plos One. Accès à la publication
2010
DNA cytosine methylation in the bovine leukemia virus promoter is associated with latency in a lymphoma-derived B-cell line: potential involvement of direct inhibition of cAMP-responsive element (CRE)-binding protein/CRE modulator/activation transcription factor binding. J Biol Chem. Accès à la publication
Molecular mechanisms of HIV-1 persistence in the monocyte-macrophage lineage. Retrovirology. Accès à la publication
[Molecular basis of HIV-1 latency - Part II: HIV-1 reactivation and therapeutic implications]. Med Science (Paris). Accès à la publication
[Molecular basis of HIV-1 latency - part I: physiology of HIV-1 latency]. Med Science (Paris). Accès à la publication
HIV-1 regulation of latency in the monocyte-macrophage lineage and in CD4+ T lymphocytes. J Leukoc Biol. Accès à la publication
2009
p21(WAF1) gene promoter is epigenetically silenced by CTIP2 and SUV39H1. Oncogene. Accès à la publication
Synergistic activation of HIV-1 expression by deacetylase inhibitors and prostratin: implications for treatment of latent infection. Plos One. Accès à la publication
2007
Recruitment of chromatin-modifying enzymes by CTIP2 promotes HIV-1 transcriptional silencing. EMBO J. Accès à la publication
2005
COUP-TF interacting protein 2 represses the initial phase of HIV-1 gene transcription in human microglial cells. Nucleic Acids res. Accès à la publication
2003
Regulation of HIV-1 gene transcription: from lymphocytes to microglial cells. J Leukoc Biol. Accès à la publication
Recruitment of Tat to heterochromatin protein HP1 via interaction with CTIP2 inhibits human immunodeficiency virus type 1 replication in microglial cells. J Virol. Accès à la publication
2000
The nuclear receptor chicken ovalbumin upstream promoter transcription factor interacts with HIV-1 Tat and stimulates viral replication in human microglial cells. J Biol Chem. Accès à la publication
Functional interactions between C/EBP, Sp1, and COUP-TF regulate human immunodeficiency virus type 1 gene transcription in human brain cells. J Virol. Accès à la publication
1999
CREB and COUP-TF mediate transcriptional activation of the human immunodeficiency virus type 1 genome in Jurkat T cells in response to cyclic AMP and dopamine. J Cell Biochem. Accès à la publication
Dopamine stimulates expression of the human immunodeficiency virus type 1 via NF-kappaB in cells of the immune system. Nucleic Acids res. Accès à la publication
1997
COUP-TF and Sp1 interact and cooperate in the transcriptional activation of the human immunodeficiency virus type 1 long terminal repeat in human microglial cells. J Biol Chem. Accès à la publication
Characterization of nuclear proteins that bind the regulatory TGATTGGC motif in the human immunodeficiency virus type 1 long terminal repeat. Nucleic Acids Res. Accès à la publication
1996
Chicken ovalbumin upstream promoter transcription factor, a transcriptional activator of HIV-1 gene expression in human brain cells. J Biol Chem. Accès à la publication
Regulation of human immunodeficiency virus type 1 gene transcription by nuclear receptors in human brain cells. J Biol Chem. Accès à la publication
